Life Threatening Bleeds in Oral Anticoagulated Patients

Noval Oral Anticoagulant (NOAC) medications. Travelers like the convenience because they don’t need monthly blood tests. It also means they show up in your emergency departments and clinics from all over the world with minor and major bleeds. How do you know what reversal agent to give or even if there is one? Perhaps they can’t recall the name or a friend is watching their belongings at the hotel.

Check out the December Annuals of Emergency Medicine podcast: Reversal of NOACs by Jessica Mason MD, Andy Grock MD and Annahieta Kalantari DO. The simple answer may surprise you.

Who knew? Hirudin extracts from the medicinal leeches were first used for parenteral anticoagulation in the clinic in 1909, but their use was limited due to adverse effects and difficulties in achieving highly purified extracts. Published by NCBI PubMed 2012 Jun 1;9(2):83-104.

 

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